Reginald Coleman studied at Cameron College under Jack Bryan. He later earned his Bachelor of Fine Arts and Master of Fine Arts at the University of Oklahoma. While attending the university, he studied with Eugene Bavinger and George Bogart. During his studies at OU, he had two one-person exhibitions at the Museum of Art of the University of Oklahoma, one was held when he was still an undergraduate student.
In 2006, he retired as professor emeritus after teaching drawing and design for thirty years at College of Lake County in Grayslake, Illinois. His work has been exhibited nationally from Minnesota to New York and Oklahoma to Ohio. His work is included in numerous collections including the Fred Jones Jr. Museum of Art at the University of Oklahoma, First Illinois Bank, and the Hollister Corporation.